Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome.
Cassani B
J Exp Med. 2010 Jun 14;207(7):1525-40. doi: 10.1084/jem.20091928
Blocking lymphocyte localization to the gastrointestinal mucosa as a therapeutic strategy for inflammatory bowel diseases.
Villablanca EJ
Gastroenterology. 140(6):1776-84. doi: 10.1053/j.gastro.2011.02.015
Gut-tropic T cells that express integrin α4β7 and CCR9 are required for induction of oral immune tolerance in mice.
Cassani B
Gastroenterology. 2011 Sep 16;141(6):2109-18. doi: 10.1053/j.gastro.2011.09.015
Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.
Pala F
J Clin Invest. 2015 Sep 14;125(10):3941-51. doi: 10.1172/JCI82249
Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects.
Rigoni R
J Exp Med. 2016 Feb 29;213(3):355-75. doi: 10.1084/jem.20151116
B lymphocytes limit senescence-driven fibrosis resolution and favor hepatocarcinogenesis in mouse liver injury.
Faggioli F
Hepatology. 2018 Mar 25;67(5):1970-1985. doi: 10.1002/hep.29636
Efficacy of lentivirus-mediated gene therapy in an Omenn syndrome recombination-activating gene 2 mouse model is not hindered by inflammation and immune dysregulation.
Capo V
J Allergy Clin Immunol. 2017 Dec 11;142(3):928-941.e8. doi: 10.1016/j.jaci.2017.11.015
The microbiome and immunodeficiencies: Lessons from rare diseases.
Pellicciotta M
J Autoimmun. 2019 Jan 28;98:132-148. doi: 10.1016/j.jaut.2019.01.008
Absence of Dipeptidyl Peptidase 3 Increases Oxidative Stress and Causes Bone Loss.
Menale C
J Bone Miner Res. 2019 Sep 9;34(11):2133-2148. doi: 10.1002/jbmr.3829
Cutaneous barrier leakage and gut inflammation drive skin disease in Omenn syndrome.
Rigoni R
J Allergy Clin Immunol. 2020 Apr 18;146(5):1165-1179.e11. doi: 10.1016/j.jaci.2020.04.005